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Duloxetine Hydrochloride

Read and learn more about Duloxetine Hydrochloride.

Q: Cymbalta ( duloxetine hydrochloride ) did it help you?
I have just been perscribed cymbalta and curious if it has actually helped because i hear alot of the time not to take anti-depressents that it makes matters worse.

A: My sister, uncle, and I all love it.It made my depression go completely away, and hindered the OCD for a while too, which was a bonus. My sister has tried dozens of meds, and she says the one which helped her the most was Cymbalta. We’re both on a high dose (120mg), but it’s worked miracles for us. I don’t know much about my uncle’s situation, except that he takes it and likes it.
I should add that all three of us are on multiple psychiatric meds
Mine: Seroquel 650mg, Cymbalta 120mg, Klonopin .5mg, Anafranil 100mg
Sister’s: Seroquel 200mg, Cymbalta 120mg, Adderall ?mg, Lithium ?mg
Uncle: Clozaril ?mg, Abilify ?mg, Cymbalta ?mg
So yeah, my uncle and I have schizophrenia, and my sister has extremely severe depression.
But the bottom line is that Cymbalta is awesome (None of us has had any side effects), and you won’t see that unless you try it.
And even if it’s not the one for you, there are plenty of other ones. I went through 5 or 6 antidepressants before finding the one that worked for me, so don’t give up trying meds until you’ve went through a few.
Good luck :)

Q: what are the side effects of ‘DUZELA’ ? (duloxetine hydrochloride)?
does this drug have any negative effect on your blood profile? esp. lowering of platelet count? or for that matter on body muscles, and does it cause fatigue in the patient too?

A: these are the same thing. check the link.
Cymbalta side effects

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Cymbalta.

Side effects may include:
Appetite changes, constipation, diarrhea, dizziness, dry mouth, fatigue, headache, insomnia, nausea, sexual difficulties, sleepiness, sweating, tremor, urinary difficulties, vomiting, weakness

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Why should Cymbalta not be prescribed?

You will not be able to use Cymbalta if it causes an allergic reaction. In addition, you should not take Cymbalta if you have uncontrolled narrow-angle glaucoma, a disease that causes increased pressure in the eyes.

Never combine Cymbalta with an MAO inhibitor such as Marplan, Nardil, or Parnate (see “Most important fact about Cymbalta”).

Do not take the drug thioridazine (Mellaril) with Cymbalta, as it could cause fatal heartbeat irregularities.

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Special warnings about Cymbalta

In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Cymbalta or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Cymbalta has not been studied in children or adolescents and is not approved for treating anyone less than 18 years old.

Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they’re taking antidepressants. Individuals being treated with Cymbalta and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly–especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior–and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.

Some medical conditions require careful monitoring during treatment with Cymbalta. Be sure to tell the doctor if you have diabetes, glaucoma, high blood pressure, or a seizure disorder. Cymbalta can cause episodes of mania (abnormally high feelings of excitement and energy), so be sure the doctor is aware if you have this condition.

Using Cymbalta is not recommended if you have liver problems or severe kidney disease.

Like other antidepressants, Cymbalta can cause drowsiness and affect judgment or motor skills. Use caution when driving, operating dangerous machinery, or participating in hazardous activities until you know how the drug affects you.

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Possible food and drug interactions when taking Cymbalta

Never take Cymbalta with MAO inhibitors (see “Most important fact about Cymbalta”) or the drug thioridazine (Mellaril). Consult your doctor first before taking drugs that act on the central nervous system, such as antipsychotics, narcotic painkillers, sleep inducers, or tranquilizers.

Due to the possibility of liver damage, do not take Cymbalta if you use alcohol more than occasionally.

If Cymbalta is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Cymbalta with the following:

Antibiotics known as quinolones, such as Cipro, Floxin, and Trovan
Antidepressants known as tricyclics, including Elavil, Pamelor, and Tofranil
Antidepressants that raise serotonin levels, such as Effexor, Paxil, Prozac, and Zoloft
Antipsychotic medication known as phenothiazines, including Compazine, Prolixin, Serentil, Thorazine, and Trilafon
Flecainide (Tambocor)
Fluvoxamine
Propafenone (Rythmol)
Quinidine

Q: what is the lethal dose of cymbalta (duloxetine hydrochloride)?

A: ummm idk but it is really hard to kill yourself or someone else on an anti-depressant….cause they are slowly released into your body through out the day….youll just end up getting sick if you take too many of them…if ur having bad thoughts….then its time that you talked to someone about how you are feeling….please get help b4 it is too late.

Q: Is it safe to take 150mg of Wellbutrin XL and 60mg of Cymbalta together? ?
(150mg Bupropion hydrochloride & 60mg duloxetine HCI)

If prescribed by a doctor? I’m just researching a prescription to see what others have to say.

A: The chemical make of the two medications are different.

This might confuse you but please hang in with me.
Wellbutrin is of the aminoketone class.
Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI).
These are two different classes of antidepressants.

Ok – if you are worried about the doses. Cymbalta is proven safe for doses up to 120mg. Wellbutrin XL is proven safe up to 450 mg.

There are many times that doctors will prescribe two antidepressants at the same time. The reasons are numerous. Need of more antidepressant effect, need of another uptake receptor medication, need to treat another issue, this list could go on almost endlessly.

You doctor is ok in prescribing the two together. Chemically there is no interaction, there is no know side effects of combining the two, they do not target the same receptors in the brain.

Q: What is the problem with taking anti depressant medication and cold/flu medication together?
Medication is called Cymbalta (duloxetine 60mg) diagnosed for anxiety, the cold medication has pseudoephedrine hydrochloride 30mg and Paracetamol 500mg & codeine phosphate 9mg. Whats the problem with taking these two meds together??

A: Ask a pharmacist…..only they will be aware of potential drug interactions. However, you have to consider you are taking a psychiatric drug that works on the neurotransmitters in your brain. Neurotransmitters in in your brain regulate EVERYTHING with your body. If you cause the wrong interactions, you could lower the threshold for seizures, and have seizures, you could seriously raise or lower your blood pressure or heart rate. And that is just a start. If you have already been told that you should not take that cold medication on the antidepressant, then dont. If you are asking if you can….ask your pharmacist.

Q: Do I have to wait a few days before switching meds?
I was taking escitalopram (5mg) and now my doctor wants me to take Cymbalta (duloxetine hydrochloride) because I was getting a lot of side effects on the escitalopram.
I’m just wondering, do I need to wait a few days to get the previous drug out of my system before taking a new one? My doctor said I could just start right away since the 5mg is such a small amount but I’m really not sure… Would it matter that I’m switching from an SSRI to an SNRI?
Any advice is helpful, thanks!

A: If your doctor thinks it won’t harm you, then I wouldn’t worry about it. If you are really worried about it, call your doctor and ask if you can wait a few days. However, anti-depressants stay in your system for several weeks, so you can’t simply wait for one to fade completely out before starting another.

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